Overview
0xyc0d0ne 80 mg (marked as OP 80) is a high-strength, extended-release (ER) opioid pain medication. It contains 0xyc0d0ne hydrochloride, an opioid analgesic used to manage severe and chronic pain requiring continuous, long-term opioid therapy.
This tablet is formulated to release the medicine slowly over 12 hours and should never be used for mild or short-term pain.
OP 80 refers to the imprint on the green, round OxyContin 80 mg tablet, manufactured by Purdue Pharma in the U.S. The “OP” mark indicates the abuse-deterrent formulation introduced to replace older “OC” tablets.
Key Facts
- Strength: 80 mg 0xyc0d0ne hydrochloride
- Form: Extended-release oral tablet
- Color/Shape: Green, round tablet imprinted with “OP 80”
- Controlled substance: Schedule II (high potential for abuse)
- Brand: OxyContin OP 80 mg
- Generic availability: Yes, but only in abuse-deterrent form
How It Works
0xyc0d0ne binds to μ-opioid receptors in the brain and spinal cord, blocking pain signals and producing pain relief.
Because it is an extended-release product, each tablet maintains pain control for up to 12 hours when taken as directed.
Important Usage Instructions
- Take exactly as prescribed by your doctor.
- Swallow the tablet whole with water — do not crush, chew, or dissolve, as this can release a potentially fatal dose.
- Usually taken every 12 hours (twice daily).
- Do not take more than prescribed, and never share your medication.
- Avoid alcohol or sedatives while using 0xyc0d0ne.
Warnings
⚠️ High risk of addiction, abuse, and overdose.
Even one tablet can be deadly if misused.
Do not use if you have:
- Severe asthma or breathing problems
- A blockage in your intestines or stomach
- Allergy to 0xyc0d0ne or similar opioids
Taking OxyContin 80 mg with alcohol, benzodiazepines, or other CNS depressants can cause fatal respiratory depression.



Common Side Effects
- Nausea or vomiting
- Constipation
- Drowsiness or dizziness
- Headache
- Dry mouth or itching
Serious Side Effects (Call for Emergency Help)
- Slow or shallow breathing
- Confusion or severe drowsiness
- Blue lips or fingernails
- Fainting or irregular heartbeat
- Seizures
- Signs of serotonin syndrome (fever, agitation, muscle stiffness)
Overdose Signs
- Extreme sleepiness
- Very slow or no breathing
- Pinpoint pupils
- Cold, clammy skin
➡️ Call emergency services (911) immediately. Administer naloxone (Narcan) if available.
Drug Interactions
Avoid combining OxyContin 80 mg with:
- Other opioids (morphine, tramadol, hydrocodone)
- Benzodiazepines (Xanax, Valium, Ativan)
- Alcohol or sleep medications
- Antidepressants or seizure drugs
- CYP3A4 inhibitors (clarithromycin, ketoconazole)
Pregnancy and Breastfeeding
- Using 0xyc0d0ne during pregnancy may cause neonatal opioid withdrawal in newborns.
- It passes into breast milk and may cause breathing problems in infants — avoid breastfeeding while taking OxyContin 80 mg.
Storage & Disposal
- Store at room temperature, away from moisture and light.
- Keep out of reach of children and others.
- Dispose of unused tablets safely via a drug take-back program or flush if no program is available.
Quick Summary
| Feature | Details |
|---|---|
| Drug Name | 0xyc0d0ne Hydrochloride ER |
| Imprint | OP 80 |
| Strength | 80 mg |
| Color/Shape | Green, round tablet |
| Brand Name | OxyContin |
| Drug Class | Opioid analgesic |
| Schedule | II (Controlled Substance) |
| Duration of Effect | ~12 hours |
| Risk | Addiction, overdose, respiratory depression |
Disclaimer
This article is for educational purposes only and is not a substitute for professional medical advice. Always consult your doctor or pharmacist before starting or changing any medication.


